Increased in magnesium intake in the diet associated with chronic pain reduction: a systematic review

Abstract

Objectives: To perform a systematic review that addresses the association between increased intake of
magnesium through diet and reduction of chronic pain. Methods: A systematic review was developed from PubMed,
BIREME and LILACS databases, via DeCS/MeSH descriptors; studies addressing the issue of magnesium intake in the
diet of individuals with chronic pain were included in the review. Using the languages English, Portuguese and Spanish.
The bibliographic survey was carried out from August to September 2018. Results: Of the total articles selected, 3 met the
inclusion criteria, 1 of which were not significant (p> 0.05). In women with fibromyalgia (FM) between 18-60 years, Mg
and Ca intake presented a positive correlation with the pain threshold (r = 0.25, p = 0.01 and r = 0.32, p = 0.01 ,
respectively) and negative correlation with TP (r = -0.23, p = 0.02 and r = -0.28, p = 0.03, respectively). Regarding the
intensity of migraine pain, it was significantly reduced in the supplementation group (magnesium, riboflavin and coezima
Q10) compared to placebo (p = 0.03). Of the 90 women with rheumatoid arthritis (RA) there was no significant
relationship between nutrient intake and disease activity score. Conclusion: There is a correlation in the increase of the
magnesium intake with the reduction of the chronic pain, reinforcing the relevance of the nutritional care to improve the
quality of life.