Frequency of symptoms in patients with suspected hyperprolactinemia admitted to a private psychiatric clinic in Recife

Authors

DOI:

https://doi.org/10.56102/afmo.2024.305

Keywords:

Antipsychotropic drugs, Hyperprolactinemia, Macroprolactinemia, Psychiatric patients

Abstract

Objective: To investigate the symptoms of patients with suspected hyperprolactinemia admitted to a private psychiatric clinic in Recife. Methods: This cross-sectional and descriptive study used non probabilistic sampling and collected data from January to March 2023 using an in-person questionnaire. Participants undergoing clinical rehabilitation for antipsychotic therapy were assessed for the presence of hyperprolactinemia. We consulted medical records to collect data on the medications in use. Data was collected using Excel 2010 and SPSS version 22.0. Results: A total of 51 hospitalized patients aged between 16 and 87 years (SD ± 18.3) were included. Approximately 25% of the participants reported symptomatology commonly associated with hyperprolactinemia, including gynecomastia (53.8%), impaired libido (38.5%), and galactorrhea (7.7%). The medications biperidenhydrochloride and quetiapine hemifumarate were the most prevalent among patients who had complaints of gynecomastia. In contrast, quetiapine hemifumarate, zolpidem hemitartrate, and alprazolam were most frequently used by those reporting impaired libido. Conclusions: This study verified the prevalence of symptoms associated with hyperprolactinemia in patients using antipsychotics admitted to a psychiatric clinic.

Author Biographies

Emilly Kelly Paiva Damasceno, Faculdade de Medicina de Olinda

Linked to the Faculdade de Medicina de Olinda. Olinda, Pernambuco, Brazil.

Gabriel José Paiva Aldeman, Faculdade de Medicina de Olinda

Holds a degree in Business Administration - Devry Brasil (2014). Has experience in the areas of Business Administration, with emphasis on Business Management. As an entrepreneur he was creator and owner of the healthy sports nutrition company - 4FitNutrition (2014), creator and partner of EatFit (2014).

Andréia Veras Gonçalves, Faculdade de Medicina de Olinda

Graduated in Medicine at the University of Pernambuco (2002). Residency in Internal Medicine at Hospital da Restauração, Residency in Endocrinology at Hospital Agamenon Magalhães, Master in Tropical Medicine at the Federal University of Pernambuco. Currently she is a doctoral candidate in the post-graduate program in Tropical Medicine, UFPE. Endocrinologist in the Surgery Program for Obesity Treatment at Hospital Universitário Oswaldo Cruz / UPE. Professor at the Olinda School of Medicine.

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Published

2024-06-28

How to Cite

Damasceno, E. K. P., Aldeman, G. J. P., & Gonçalves, A. V. (2024). Frequency of symptoms in patients with suspected hyperprolactinemia admitted to a private psychiatric clinic in Recife. Annals of Olinda Medical School, 1(11), 68–77. https://doi.org/10.56102/afmo.2024.305

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Section

Original Articles