High-grade squamous intraepithelial lesion of the vulva secondary to human papillomavirus in a 54-year-old patient
a case report
DOI:
https://doi.org/10.56102/afmo.2025.385Keywords:
Intraepithelial lesion, Vulva, HPV, NeoplasmAbstract
Vulvar high-grade squamous intraepithelial lesion (HSIL) is a premalignant condition often associated with human papillomavirus that may progress to carcinoma. This study reports the case of a 54-year-old asymptomatic woman diagnosed with vulvar HSIL during a routine gynecological examination. Histopathological analysis confirmed the diagnosis, revealing an usual and multifocal vulvar intraepithelial neoplasia grade 3 (VIN3). This case evidences the essential role of anamnesis and physical examination. The selected treatment was the loop electrosurgical excision of the affected area identified by vulvoscopy, ensuring adequate safety margins. To maintain vulvar aesthetics, the procedure was followed by vulvoplasty.
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Copyright (c) 2025 Fernando Augusto Pacífico, Assíria de Holanda Gama, Pollyanna Alves da Silva, Rayra Luiza Araújo de Lira, Yasmin Iza Cotting, Angelina Farias Maia, Petrus Augusto Dornelas Câmara
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